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What is the biochemical explanation for why G6PD deficiencies are so prevalent in Africa?G6PD deficiencies result in elevated cellular ROS because of limiting NADPH; malarial parasites cannot survive in a high ROS environmentG6PD deficiencies result in elevated cellular ROS because of limiting NADH; malarial parasites cannot survive in a low ROS environment.G6PD deficiencies result in elevated NADPH levels, which are toxic to malarial parasites because the reducing power of NADPH is elevated.G6PD deficiencies result in elevated cellular ROS because of limiting NADPH; malarial parasites cannot survive with high levels of NADP+.G6PD deficiencies result in elevated levels of reduced glutathione; malarial parasites can only survive when GS-SG levels are elevated.

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