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Use of Animals in Exercise Science Research Institutional Animal Care and Use Committee (IACUC) - Rigor of animal use oversight committees often exceeds those protecting humans- The knowledge to be gained must be useful enough to justify the use of animals- Investigator must demonstrate assessment of the three Rs:- Reduction • Limit the number of animals used - Refinement • Eliminate pain and stress to animals - Replacement • Defend use of animal model (why are you using it)

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