Systemic mycosess. endemic mycosesRequirements/Factorsnecessarytocausethisinfection;- Primary infection; causative agents present in soil in these endemic regions & person who is not immune compromised can be infected- Dimorphic causative agentso Infections initiated in lungs following inhalation ofconidia, later may involve dissemination from lungs- Coccidioidomycosis- Histoplasmosis- Blastomycosis- ParacoccidioidomycosisPathogenesis:- Inhalation of conidia (dimorphic soil saprophyte)→lung form (yeast like cells)→ reach bloodstream→dissemination to other organs (brain, heart, bones etc.)

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