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Structurally, the blood-brain barrier exists becauseA) the endothelial cells lining the CNS are extensively interconnected by tight junctions.B) normal blood flow is at a pressure too high for the delicate brain tissue.C) only water-soluble compounds are permitted to enter by passive diffusion.D) the hypothalamus regulates the permeability of the blood vessels.E) None of the answers are correct.

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