sickle cell anaemia:- _______ ___ mutation- involves change in sequence of ____ within the gene for ___________- codes for haemoglobin S (HbS) instead of normal haemoglobin A (HbA) - differs by ______, leading to a difference in the ________- HbS molecules ______ at _______, making the cells ____-shaped- these red blood cells cannot _____ as efficiently as normal red blood cells as they are ____ and ____, and get ____ in __________- this _____ / ____ the flow of _____ to other parts of the body

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