Pharmacogenetics is the study of how inherited genetic differences influence the inter- individual variation in the response to drugs.Which one of the following statements concerning pharmacogenetics is true?☐ A. Pharmacogenetic differences explain most of the variation in the response to drugs. ☐ B. Pharmacogenetics is the study of variability in drug response determined by thecombined effect of multiple genes☐ C. Polymorphism is a genetic variation that is observed at a frequency of >50% in a population.☐ D. Potentially important pharmacogenetic polymorphisms that affect drug response are typically discovered by mass genetic screening of candidate genes.☐ E. Single nucleotide polymorphisms are the most commonly occurring genetic differences responsible for variation in drug response.

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