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PCR kan öka mängden DNA ex vid fynd på en brottsplats. Primers anger vart kopieringen ska börja och sluta. Primers är korta enkelsträngade bitar av DNA som kan tillverkas på konstgjord väg. Man måste veta de första basparen i ändarna av den del man vill kopiera. Man tillsätter ett enzym som kan läsa koden där primern slutar och bygga på med kvävebaser. Byggs då en kopia av den DNA del man vill ha i större mängd.
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