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Or parmi les gènes mdf dans les cell tumorales, certains codent pour des Facteurs angiogéniques (VEGF) qui diffusent dans l'env et gagnent les vaisseaux et les caplr pour se fixer sur des rc-Tyr kinase => commande formation nvx vasx (néovascularisation commandée par les cell tumorales pour former de nvs vasx apportant donc plus de nutriments, oxygènene) pour que la cell grossise et forme des métastase

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