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Neutropenia pathogenesis:Decreased granulocyte production: - Certain drugs (cancer _____) - most common cause - Marrow _____ (aplastic anemia) - Extensive replacement of marrow by _____ (leukemia)Increased granulocyte destruction: - _____-mediated injury (drugs, SLE) - Increased _____ use (bacterial, fungal infections) - _____

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