Name: 2nd generation H1 antagonists: Cetirizine (Zyrtec), fexofenadine (Allegra) (ZyrAll box name, H1 with block/antagonize)MOA: non-sedating antihistamines that antagonize H1 receptors without crossing the blood brain barrier (Stop-BBB card, Hand in face with red inhibit marks at head, Zzzz crossed out, don't sleep on this box)Clinical: Treatment of allergic rhinitis (Card with nose with rhinitis)ADME: Formulated to be charged at physiological pH, preventing entry into the CNS. Metabolized by CYPs, so cautious with drug interactions. All oral except olapatadine, which is an eye drop (Card with PH of philly, and CYP in crowd)AE: Well tolerated (New, no AE)

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