Most enzymes in the human body work best at neutral pH. Select the reasons why changing the pH of the fluid in which a human enzyme is dissolved (for example to a pH of 3) will affect the enzyme's ability to function.Multiple select question.The enzyme loses its side chains at an extreme pH, such as a pH of 3.The enzyme is dissolved into amino acids.The balance between positively and negatively charged amino acids in the enzyme is shifted.Enzymes cannot maintain their three-dimensional shape at extreme pHs, such as a pH of 3.

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