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- Lack of cell wall (not susceptable to beta-lactam and glycopeptide antibiotics, sensitive to macrolides, tetracyclines, fluoroquinolones)- They are highly pleomorphic.- Multiply by binary fission- They are bounded by a tripple-layered cell membrane that contains sterols. Sterols are critical components of the mycolpasma cell membrane that provide stability and structural support.- Are cultivated in artificial media with sterols (microcolonies - «fried eggs» appearance)- No spores, no capsule, no flagella- Contain both nucleid acids: DNA and RNA

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