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La muqueuse est formée d'un épithélium pseudostratifié cilié avec des cellules caliciformes dans sa partie respiratoire et de type épidermoïde dans sa portion digestive. Le derme est composé d'un tissu conjonctif riche en fibres élastiques. Dans la partie digestive, le derme comporte du tissu lymphoïde, le MALT renfermant les amygdales ainsi que des glandes salivaires accessoires.

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