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La 15-15'-dioxygénase coupe le β-carotène sur la double liaison en son centre (C15-C16 = C15-C15')Les 2 rétinals ainsi créés peuvent être réduits en rétinol et intégrer les chylomicrons sous forme d'ester.Les 2 rétinals peuvent aussi être oxydés en acide rétinoïques.

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