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Homozygotes with two sickle-cell alleles are selected against because of mortality. However, heterozygotes for sickle-cell allele experience little effects of sickle allele and are more likely to survive malaria. The net effect of this exposure produced evolutionary change in areas where malaria is endemic by ________.a) causing sickle-cell alleleb) increasing sickle-cell frequencyc) distortion of red blood cellsd) increasing the number of infected mosquitoes

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