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Histone acetyltransferase (HAT) and histone deacetylase (HDAC) add and remove acetyl groups on histone tails, respectively. DNA methyltransferase (DNMT) adds methyl groups on the cytosine in DNA. Therefore, which of the following mutations is related to an increase of gene expression?Mutation #1: Loss-of-function mutations on HATMutation #2: Loss-of-function mutations on HDACMutation #3: Loss-of-function mutations on DNMT

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