Epigenetic of obesity:- Histone modifications: _____ acetylation of H3K9 (histone 3 lysine 9) at _____ gene; _____ acetylation of H3K9 at _____ (neuropeptide Y)- DNA methylation: Negative association between body weight and DNA methylation of leptin promotor; Increased POMC _____ levels; Decreased NPY _____ levels - Non-coding RNA: _____ (miR-21, miR-199a): increased insulin _____; altered _____ levels - Environmental factors: _____ exposures (_____ --> Methylation of IGF-2 receptor gene --> Insulin growth factor 2 --> Silenced); Dietary factors; Physical activity

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