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Assuming PAO₂ is a balance between O₂ consumption & alveolar ventilation just as PACO₂ is related to alveolar ventilation (inversely), one can calculate PAO₂ using the alveolar gas equation.Also, a simple way to approximate PAO₂ is to multiply the FiO₂ by 6.-If FiO₂ is 0.4, then 40% x 6 = 240 mmHg (assuming no pathologies)

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