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Analysis of fetal samples: - _____ villus sampling: 11-12 weeks (1st trimester) - _____: 15-16 weeks (early 2nd trimester) - _____ _____ and _____: late gestation through ultrasound-guided percutaneous umbilical blood sampling (PUBS, 3rd trimester) - Preimplantation genetic diagnosis: genetic diagnoses in pre-implantation human embryos

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