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A 69 year old man presents with recent onset of weight loss. He has a past history of bladder, prostateand bowel cancer. He has no other significant symptoms and his examination is unremarkable. Testingfor which of the following tumour markers would be of the greatest benefit in determining whetherinvestigation for malignancy is required?A beta-HCGB prostate specific antigenC alpha feto-proteinD CA 15-3E S-100 protein

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