The ____________, negotiated by Henry Clay, provided that Missouri would enter the Union as a slave state and Maine as a free state. It also drew a line at 36 degrees 30 minutes across the area of the original Louisiana Purchase (and ONLY the Louisiana Purchase). The Compromise prohibited slavery north of that line (except in Missouri) and allowed it south of the line. Note that the Missouri Compromise did not apply to states east of the Louisiana Purchase, or to the vast area under Spanish (and then Mexican rule) that lay west of the Louisiana Purchase in 1820. After the compromise, politicians agreed to try to keep the issue of slavery out of American politics.

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