1823 - Declared that Europe should not interfere in the affairs of the Western Hemisphere and that any attempt at interference by a European power would be seen as a threat to the U.S. It also declared that a New World colony which has gained independence may not be recolonized by Europe. (It was written at a time when many South American nations were gaining independence). Only England, in particular George Canning, supported the Monroe Doctrine. Mostly just a show of nationalism, the doctrine had no major impact until later in the 1800s.

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